People living with MGUS receive regular checkups to ensure that it does not progress. MGUS usually does not cause any problems or require treatment, but in rare cases (1%-2%), it can develop into multiple myeloma. MGUS occurs in about 1% of the general population. MGUS is a plasma cell neoplasm diagnosed when a small amount of M protein is detected in the blood, but no other criteria for a solitary plasmacytoma or multiple myeloma diagnosis (such as a tumor, multiple lesions or symptoms) are present. Monoclonal gammopathy of undetermined significance (MGUS)
Classification also plays an important role in determining the stage of multiple myeloma. Knowing the classification of your disease is very important in deciding when it is appropriate to begin treatment.
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